glucose (glc Search Results


ugdh  (Proteintech)
93
Proteintech ugdh
Fig. 7. ROS activate the PI3K/AKT pathway, regulating <t>the</t> <t>UGDH-EEF1A2-PRDX1</t> axis to promote chemoresistance. (A) KEGG pathway enrichment of DEGs in UGDH-knockdown SW620 cells (n = 3 replicates). (B) Western blot of PI3K/AKT pathway proteins in HCT8 cells ± LY294002 (10 μM, 48 h, n = 3). (C) PI3K/AKT phosphorylation in HCT8 control and shUGDH cells ± 5-FU (n = 3). (D) UGDH and PI3K/AKT activation in HCT8 cells treated with H2O2 (0–200 μM, 24 h, n = 3). (E) Time-dependent UGDH activation in HCT8 cells treated with 15 μM 5-FU (0–96 h). (n = 3). (F) Western blot of PI3K/AKT pathway proteins in HCT8 cells ± LY294002 (10 μM, n = 3)/± NAC (750 μМ, n = 3). Data are mean ± SD. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001.
Ugdh, supplied by Proteintech, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/glucose+(glc/UGDH+Antibody/pm40311992-81-6-7
Average 93 stars, based on 1 article reviews
ugdh - by Bioz Stars, 2026-09
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maltotriose  (Aladdin Scientific Corporation)
94
Aladdin Scientific Corporation maltotriose
Fig. 7. ROS activate the PI3K/AKT pathway, regulating <t>the</t> <t>UGDH-EEF1A2-PRDX1</t> axis to promote chemoresistance. (A) KEGG pathway enrichment of DEGs in UGDH-knockdown SW620 cells (n = 3 replicates). (B) Western blot of PI3K/AKT pathway proteins in HCT8 cells ± LY294002 (10 μM, 48 h, n = 3). (C) PI3K/AKT phosphorylation in HCT8 control and shUGDH cells ± 5-FU (n = 3). (D) UGDH and PI3K/AKT activation in HCT8 cells treated with H2O2 (0–200 μM, 24 h, n = 3). (E) Time-dependent UGDH activation in HCT8 cells treated with 15 μM 5-FU (0–96 h). (n = 3). (F) Western blot of PI3K/AKT pathway proteins in HCT8 cells ± LY294002 (10 μM, n = 3)/± NAC (750 μМ, n = 3). Data are mean ± SD. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001.
Maltotriose, supplied by Aladdin Scientific Corporation, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/glucose+(glc/Maltotriose/pmc12785547-85-12-17
Average 94 stars, based on 1 article reviews
maltotriose - by Bioz Stars, 2026-09
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cellobiose  (Chem Impex International)
95
Chem Impex International cellobiose
Fig. 7. ROS activate the PI3K/AKT pathway, regulating <t>the</t> <t>UGDH-EEF1A2-PRDX1</t> axis to promote chemoresistance. (A) KEGG pathway enrichment of DEGs in UGDH-knockdown SW620 cells (n = 3 replicates). (B) Western blot of PI3K/AKT pathway proteins in HCT8 cells ± LY294002 (10 μM, 48 h, n = 3). (C) PI3K/AKT phosphorylation in HCT8 control and shUGDH cells ± 5-FU (n = 3). (D) UGDH and PI3K/AKT activation in HCT8 cells treated with H2O2 (0–200 μM, 24 h, n = 3). (E) Time-dependent UGDH activation in HCT8 cells treated with 15 μM 5-FU (0–96 h). (n = 3). (F) Western blot of PI3K/AKT pathway proteins in HCT8 cells ± LY294002 (10 μM, n = 3)/± NAC (750 μМ, n = 3). Data are mean ± SD. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001.
Cellobiose, supplied by Chem Impex International, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/glucose+(glc/D(%2B)-Cellobiose/pm37463861-46-29-35
Average 95 stars, based on 1 article reviews
cellobiose - by Bioz Stars, 2026-09
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methyl α d glucopyranoside  (Chem Impex International)
95
Chem Impex International methyl α d glucopyranoside
Fig. 7. ROS activate the PI3K/AKT pathway, regulating <t>the</t> <t>UGDH-EEF1A2-PRDX1</t> axis to promote chemoresistance. (A) KEGG pathway enrichment of DEGs in UGDH-knockdown SW620 cells (n = 3 replicates). (B) Western blot of PI3K/AKT pathway proteins in HCT8 cells ± LY294002 (10 μM, 48 h, n = 3). (C) PI3K/AKT phosphorylation in HCT8 control and shUGDH cells ± 5-FU (n = 3). (D) UGDH and PI3K/AKT activation in HCT8 cells treated with H2O2 (0–200 μM, 24 h, n = 3). (E) Time-dependent UGDH activation in HCT8 cells treated with 15 μM 5-FU (0–96 h). (n = 3). (F) Western blot of PI3K/AKT pathway proteins in HCT8 cells ± LY294002 (10 μM, n = 3)/± NAC (750 μМ, n = 3). Data are mean ± SD. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001.
Methyl α D Glucopyranoside, supplied by Chem Impex International, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/glucose+(glc/Methyl-a-D-glucopyranoside/pm36309312-82-15-61
Average 95 stars, based on 1 article reviews
methyl α d glucopyranoside - by Bioz Stars, 2026-09
95/100 stars
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octyl β d glucopyranoside  (Chem Impex International)
95
Chem Impex International octyl β d glucopyranoside
Fig. 7. ROS activate the PI3K/AKT pathway, regulating <t>the</t> <t>UGDH-EEF1A2-PRDX1</t> axis to promote chemoresistance. (A) KEGG pathway enrichment of DEGs in UGDH-knockdown SW620 cells (n = 3 replicates). (B) Western blot of PI3K/AKT pathway proteins in HCT8 cells ± LY294002 (10 μM, 48 h, n = 3). (C) PI3K/AKT phosphorylation in HCT8 control and shUGDH cells ± 5-FU (n = 3). (D) UGDH and PI3K/AKT activation in HCT8 cells treated with H2O2 (0–200 μM, 24 h, n = 3). (E) Time-dependent UGDH activation in HCT8 cells treated with 15 μM 5-FU (0–96 h). (n = 3). (F) Western blot of PI3K/AKT pathway proteins in HCT8 cells ± LY294002 (10 μM, n = 3)/± NAC (750 μМ, n = 3). Data are mean ± SD. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001.
Octyl β D Glucopyranoside, supplied by Chem Impex International, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/glucose+(glc/n-Octyl-b-D-glucopyranoside/pmc04843474-367-0-6
Average 95 stars, based on 1 article reviews
octyl β d glucopyranoside - by Bioz Stars, 2026-09
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uridine  (Valiant Co Ltd)
94
Valiant Co Ltd uridine
Fig. 7. ROS activate the PI3K/AKT pathway, regulating <t>the</t> <t>UGDH-EEF1A2-PRDX1</t> axis to promote chemoresistance. (A) KEGG pathway enrichment of DEGs in UGDH-knockdown SW620 cells (n = 3 replicates). (B) Western blot of PI3K/AKT pathway proteins in HCT8 cells ± LY294002 (10 μM, 48 h, n = 3). (C) PI3K/AKT phosphorylation in HCT8 control and shUGDH cells ± 5-FU (n = 3). (D) UGDH and PI3K/AKT activation in HCT8 cells treated with H2O2 (0–200 μM, 24 h, n = 3). (E) Time-dependent UGDH activation in HCT8 cells treated with 15 μM 5-FU (0–96 h). (n = 3). (F) Western blot of PI3K/AKT pathway proteins in HCT8 cells ± LY294002 (10 μM, n = 3)/± NAC (750 μМ, n = 3). Data are mean ± SD. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001.
Uridine, supplied by Valiant Co Ltd, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/glucose+(glc/Uridine-5'-diphosphoglucose/bio_rxiv__64898__2025__12__06__692756-249-26-29
Average 94 stars, based on 1 article reviews
uridine - by Bioz Stars, 2026-09
94/100 stars
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d(+) glucose monohydrate  (honeywell international)
90
honeywell international d(+) glucose monohydrate
Fig. 7. ROS activate the PI3K/AKT pathway, regulating <t>the</t> <t>UGDH-EEF1A2-PRDX1</t> axis to promote chemoresistance. (A) KEGG pathway enrichment of DEGs in UGDH-knockdown SW620 cells (n = 3 replicates). (B) Western blot of PI3K/AKT pathway proteins in HCT8 cells ± LY294002 (10 μM, 48 h, n = 3). (C) PI3K/AKT phosphorylation in HCT8 control and shUGDH cells ± 5-FU (n = 3). (D) UGDH and PI3K/AKT activation in HCT8 cells treated with H2O2 (0–200 μM, 24 h, n = 3). (E) Time-dependent UGDH activation in HCT8 cells treated with 15 μM 5-FU (0–96 h). (n = 3). (F) Western blot of PI3K/AKT pathway proteins in HCT8 cells ± LY294002 (10 μM, n = 3)/± NAC (750 μМ, n = 3). Data are mean ± SD. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001.
D(+) Glucose Monohydrate, supplied by honeywell international, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/glucose+(glc/d++++glucose++glc/pmc09662914-81-35-40
Average 90 stars, based on 1 article reviews
d(+) glucose monohydrate - by Bioz Stars, 2026-09
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glucose (glc)  (Sinopharm ltd)
90
Sinopharm ltd glucose (glc)
Fig. 7. ROS activate the PI3K/AKT pathway, regulating <t>the</t> <t>UGDH-EEF1A2-PRDX1</t> axis to promote chemoresistance. (A) KEGG pathway enrichment of DEGs in UGDH-knockdown SW620 cells (n = 3 replicates). (B) Western blot of PI3K/AKT pathway proteins in HCT8 cells ± LY294002 (10 μM, 48 h, n = 3). (C) PI3K/AKT phosphorylation in HCT8 control and shUGDH cells ± 5-FU (n = 3). (D) UGDH and PI3K/AKT activation in HCT8 cells treated with H2O2 (0–200 μM, 24 h, n = 3). (E) Time-dependent UGDH activation in HCT8 cells treated with 15 μM 5-FU (0–96 h). (n = 3). (F) Western blot of PI3K/AKT pathway proteins in HCT8 cells ± LY294002 (10 μM, n = 3)/± NAC (750 μМ, n = 3). Data are mean ± SD. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001.
Glucose (Glc), supplied by Sinopharm ltd, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/glucose+(glc/glucose++glc+/pmc06403953-35-23-25
Average 90 stars, based on 1 article reviews
glucose (glc) - by Bioz Stars, 2026-09
90/100 stars
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uridine diphosphate glucose (udp-glc)  (NEN Life Science)
90
NEN Life Science uridine diphosphate glucose (udp-glc)
Fig. 7. ROS activate the PI3K/AKT pathway, regulating <t>the</t> <t>UGDH-EEF1A2-PRDX1</t> axis to promote chemoresistance. (A) KEGG pathway enrichment of DEGs in UGDH-knockdown SW620 cells (n = 3 replicates). (B) Western blot of PI3K/AKT pathway proteins in HCT8 cells ± LY294002 (10 μM, 48 h, n = 3). (C) PI3K/AKT phosphorylation in HCT8 control and shUGDH cells ± 5-FU (n = 3). (D) UGDH and PI3K/AKT activation in HCT8 cells treated with H2O2 (0–200 μM, 24 h, n = 3). (E) Time-dependent UGDH activation in HCT8 cells treated with 15 μM 5-FU (0–96 h). (n = 3). (F) Western blot of PI3K/AKT pathway proteins in HCT8 cells ± LY294002 (10 μM, n = 3)/± NAC (750 μМ, n = 3). Data are mean ± SD. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001.
Uridine Diphosphate Glucose (Udp Glc), supplied by NEN Life Science, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/glucose+(glc/uridine+diphosphate+glucose++udp+glc+/pm15590150-43-0-7
Average 90 stars, based on 1 article reviews
uridine diphosphate glucose (udp-glc) - by Bioz Stars, 2026-09
90/100 stars
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glucose (glc)  (Merck KGaA)
90
Merck KGaA glucose (glc)
Fig. 7. ROS activate the PI3K/AKT pathway, regulating <t>the</t> <t>UGDH-EEF1A2-PRDX1</t> axis to promote chemoresistance. (A) KEGG pathway enrichment of DEGs in UGDH-knockdown SW620 cells (n = 3 replicates). (B) Western blot of PI3K/AKT pathway proteins in HCT8 cells ± LY294002 (10 μM, 48 h, n = 3). (C) PI3K/AKT phosphorylation in HCT8 control and shUGDH cells ± 5-FU (n = 3). (D) UGDH and PI3K/AKT activation in HCT8 cells treated with H2O2 (0–200 μM, 24 h, n = 3). (E) Time-dependent UGDH activation in HCT8 cells treated with 15 μM 5-FU (0–96 h). (n = 3). (F) Western blot of PI3K/AKT pathway proteins in HCT8 cells ± LY294002 (10 μM, n = 3)/± NAC (750 μМ, n = 3). Data are mean ± SD. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001.
Glucose (Glc), supplied by Merck KGaA, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/glucose+(glc/glucose++glc+/pmc11265571-61-69-95
Average 90 stars, based on 1 article reviews
glucose (glc) - by Bioz Stars, 2026-09
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dmem glucose-free (-glc  (PAN - Biotech)
90
PAN - Biotech dmem glucose-free (-glc
Fig. 7. ROS activate the PI3K/AKT pathway, regulating <t>the</t> <t>UGDH-EEF1A2-PRDX1</t> axis to promote chemoresistance. (A) KEGG pathway enrichment of DEGs in UGDH-knockdown SW620 cells (n = 3 replicates). (B) Western blot of PI3K/AKT pathway proteins in HCT8 cells ± LY294002 (10 μM, 48 h, n = 3). (C) PI3K/AKT phosphorylation in HCT8 control and shUGDH cells ± 5-FU (n = 3). (D) UGDH and PI3K/AKT activation in HCT8 cells treated with H2O2 (0–200 μM, 24 h, n = 3). (E) Time-dependent UGDH activation in HCT8 cells treated with 15 μM 5-FU (0–96 h). (n = 3). (F) Western blot of PI3K/AKT pathway proteins in HCT8 cells ± LY294002 (10 μM, n = 3)/± NAC (750 μМ, n = 3). Data are mean ± SD. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001.
Dmem Glucose Free ( Glc, supplied by PAN - Biotech, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/glucose+(glc/dmem+glucose+free+++glc/bio_rxiv__2024__03__27__586977-176-33-36
Average 90 stars, based on 1 article reviews
dmem glucose-free (-glc - by Bioz Stars, 2026-09
90/100 stars
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l -glucose (l-glc)  (Carl Roth GmbH)
90
Carl Roth GmbH l -glucose (l-glc)
Fig. 7. ROS activate the PI3K/AKT pathway, regulating <t>the</t> <t>UGDH-EEF1A2-PRDX1</t> axis to promote chemoresistance. (A) KEGG pathway enrichment of DEGs in UGDH-knockdown SW620 cells (n = 3 replicates). (B) Western blot of PI3K/AKT pathway proteins in HCT8 cells ± LY294002 (10 μM, 48 h, n = 3). (C) PI3K/AKT phosphorylation in HCT8 control and shUGDH cells ± 5-FU (n = 3). (D) UGDH and PI3K/AKT activation in HCT8 cells treated with H2O2 (0–200 μM, 24 h, n = 3). (E) Time-dependent UGDH activation in HCT8 cells treated with 15 μM 5-FU (0–96 h). (n = 3). (F) Western blot of PI3K/AKT pathway proteins in HCT8 cells ± LY294002 (10 μM, n = 3)/± NAC (750 μМ, n = 3). Data are mean ± SD. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001.
L Glucose (L Glc), supplied by Carl Roth GmbH, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/glucose+(glc/l++glucose++l+glc+/pmc08821481-38-24-49
Average 90 stars, based on 1 article reviews
l -glucose (l-glc) - by Bioz Stars, 2026-09
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Image Search Results


Fig. 7. ROS activate the PI3K/AKT pathway, regulating the UGDH-EEF1A2-PRDX1 axis to promote chemoresistance. (A) KEGG pathway enrichment of DEGs in UGDH-knockdown SW620 cells (n = 3 replicates). (B) Western blot of PI3K/AKT pathway proteins in HCT8 cells ± LY294002 (10 μM, 48 h, n = 3). (C) PI3K/AKT phosphorylation in HCT8 control and shUGDH cells ± 5-FU (n = 3). (D) UGDH and PI3K/AKT activation in HCT8 cells treated with H2O2 (0–200 μM, 24 h, n = 3). (E) Time-dependent UGDH activation in HCT8 cells treated with 15 μM 5-FU (0–96 h). (n = 3). (F) Western blot of PI3K/AKT pathway proteins in HCT8 cells ± LY294002 (10 μM, n = 3)/± NAC (750 μМ, n = 3). Data are mean ± SD. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001.

Journal: Archives of biochemistry and biophysics

Article Title: UGDH promotes 5-fluorouracil resistance in colorectal cancer via the ROS-activated PI3K/AKT-EEF1A2-PRDX1 pathway.

doi: 10.1016/j.abb.2025.110445

Figure Lengend Snippet: Fig. 7. ROS activate the PI3K/AKT pathway, regulating the UGDH-EEF1A2-PRDX1 axis to promote chemoresistance. (A) KEGG pathway enrichment of DEGs in UGDH-knockdown SW620 cells (n = 3 replicates). (B) Western blot of PI3K/AKT pathway proteins in HCT8 cells ± LY294002 (10 μM, 48 h, n = 3). (C) PI3K/AKT phosphorylation in HCT8 control and shUGDH cells ± 5-FU (n = 3). (D) UGDH and PI3K/AKT activation in HCT8 cells treated with H2O2 (0–200 μM, 24 h, n = 3). (E) Time-dependent UGDH activation in HCT8 cells treated with 15 μM 5-FU (0–96 h). (n = 3). (F) Western blot of PI3K/AKT pathway proteins in HCT8 cells ± LY294002 (10 μM, n = 3)/± NAC (750 μМ, n = 3). Data are mean ± SD. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001.

Article Snippet: The primary antibodies used were against UGDH (Proteintech), EEF1A2 (Proteintech), PRDX1 (Proteintech), PI3K (CST), phospho-PI3K (CST), Akt (CST), phospho-AKT (Ser473) (CST), FLAG (Proteintech), β-ACTIN (Proteintech), GAPDH (Beyotime), cleaved caspase 3 (CST), and cleaved PARP (CST).

Techniques: Knockdown, Western Blot, Phospho-proteomics, Control, Activation Assay